Red Roof PLUS+ Gainesville Red Roof Inn Plus Gainesville

3500 Southwest 42nd Street, Gainesville, FL   Directions
(590 Reviews)
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Ready to book? Give us a call at 1-937-328-1598 .

Hotel Overview

Adding more WOW to your stay! Red Roof PLUS+ Gainesville invites you to stay in our 100% smoke-free rooms as you experience all Gainesville has to offer. Located just three miles from the UF Health, VF Vet Hospital and the University of Florida. Close to all the sporting events: Swamp and O'Connel Center, football, basketball, archery, baseball, soccer, and drag racing. Enjoy the many features of the property including flat screen TVs, free Wi-Fi, and free local and long distance telephone calls in all rooms. There are many dining options nearby.

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Click here to experience more of Gainesville.

Experience Red Roof PLUS+. Adding more WOW to your stay! Discover an enhanced experience with our most requested higher-end amenities. Red Roof PLUS+ Gainesville, Florida is a 100% smoke-free, pet-friendly, family-friendly hotel. This hotel is close to I-75 at exit 384, the University of Florida, Santa Fe College, Kanapa Botanical Gardens, the Fred Bear Museum, the Performing Arts Center, Thr Florida Museum of Natrual History, Samuel Harn Museum of Art, Millhopper Devils Geological site, Hippodrome State Theatre, Gainesville Auto Plus Raceway, Oaks Mall, Butler Shopping Centers, UF Health, North Florida Regional Hospital, UF Vet Hospital and the VA Hospital.

As our guest you will experience our NextGen® design rooms! The rooms at this 100% smoke-free inn feature a stylish, boutique design furniture, spa-inspired bathrooms with modern vessel sinks, comfy Rest Suite beds by Serta, plush high-end bedding, modern design flooring, comfortable seating and a large, flat screen TV. This Red Roof PLUS+ hotel also features Premium Rooms with breakfast and a snack ready in your room! Red Roof PLUS+ Gainesville offers an outdoor pool that is open year around and select rooms offer microwave and mini-refrigerator units. This location includes interior corridors, an elevator, and suites. Experience our free coffeehouse-style coffee and tea. Stay connected with free Wi-Fi and keep your valuables secure in our in-room safe. This location offers “On Command Video” with a selection of free TV channels, pay-to-view premium channels, movies, music and games. We welcome your pet as a guest and one well behaved pet stays free. Welcome to Gainesville and we invite you to be our guest at the Red Roof PLUS+ Gainesville.

Learn more about Red Roof PLUS+ Gainesville!

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Key Amenities

100% Smoke Free
Kids and Pets Stay Free
Verified Wi-Fi

Hotel Amenities

  • Free Coffee in the Lobby
  • Free Expanded Cable
  • Free Long Distance
  • Bilingual/Multilingual Staff
  • Swimming Pool
  • 100% Smoke-Free
  • ADA Accessible Parking
  • ADA Accessible Rooms
  • Airport within 10 Miles
  • Elevator
  • Interior Corridors
  • Portable Cribs Available
  • Restaurant within Walking Distance
  • Snack Center
  • Free Parking


  • Target (0.18 mi)
  • Florida Museum Of Natural Historty (1.44 mi)
  • Curtis M. Phillips Center for the Performing Arts (1.46 mi)
  • Harn Museum of Art (1.51 mi)
  • Kanapaha Botanical Gardens (1.43 mi)
  • University of Florida (2.49 mi)
  • UF Veterinary Hospitals (2.38 mi)
  • Malcom Randall VA Medical Center (2.75 mi)
  • Stephen C. O'Connell Center (2.95 mi)
  • Ben Hill Griffin Stadium (3.06 mi)
  • Gainesville Regional Airport (GNV) (8.02)  mi
  • Menchie's Frozen Yogurt (0.38)  mi
  • Culver's (0.36)  mi
  • Jimmy John's (0.38)  mi
  • Pizza Hut Express (0.18)  mi
  • Steak 'n Shake (0.14)  mi
  • Maple Street Biscuit Company - Gainesville (0.37)  mi
  • Arby's (0.26)  mi
  • Miller's Ale House - Gainesville (0.29)  mi
  • McDonald's (0.24)  mi
  • Texas Roadhouse (0.38)  mi

TripAdvisor Ratings

March 13, 2018

I spend much time up and down Florida in large and small cities. This hotel is clean, and in a perfect location for restaurant access. One of the best features is the very reasonable rates for the location. It's right off of I-75 for easy access but also means highway noise. Small price to pay as far as I am concerned. Nice large flat screens with easy HDMI hook-up if you bring a gaming console and the WIFI streams nicely.

We had a very special experience at the Red Roof.
March 01, 2018

Our room was clean and close to the door for taking our puppy out. We met many pet lovers and felt welcomed and valued. But the best part of our experience was Mary. We asked for directions for a place to get a quick bite to eat and Mary, at the end of her shift and with a full hotel, offered to drive us there...offered to drive us back and made sure we were clear about how to get back when we wanted to walk. She was a delightful, charming and caring manager and made our day. I'd come back here in a heartbeat!

Budget Hotel, clean and comfortable
February 28, 2018

Generally when I visit Gainesville, I stay with family or friends. For this meeting, that was not possible so I chose this hotel to save some money. It was clean. The room was a good size and so was the bathroom. With the budget option, the towels and sheets are not the same quality. No restaurant but lots of food choices nearby. The only negative is that this is near the interstate so there is traffic noise. Just bring ear plugs and you will be fine.

Convenient, close to shopping and restaurants
February 19, 2018

Clean remodeled rooms at a fair price. Located just off i75 but quiet. A shopping mall and restaurants are located just across the street easy walking distance. Plenty of parking, park in the back or around the pool to avoid front entrance congestion and other cars.

An excellent stay, nice and clean and quiet.
February 08, 2018

First time guest, excellent stay. Very good pricing. Pets are welcome with no extra charge. The room was spotless, the bed was comfortable, the common areas were super clean, and well and the grounds surrounding the hotel. Everyone I deal with at the front desk were friendly and knowledgeable. LOADS of places to eat in the area, and just a couple of minutes off of I-75. I will recommend the Red Roof Plus+ Gainesville to my family and friends.

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See Terms & Policies

Check-in Age: 18 years or older

Pet Policy: One well-behaved family pet is permitted, at no additional charge. Pet must be declared during guest registration and kept on a leash when outside guest room. In consideration of all guests, pets must never be left unattended in the guest room. When you walk your pet on the property, please be considerate and clean up after your pet.

Safe Usage Fee of $1.50 + tax per night will be added at the hotel

Special Policy: All guest must present a valid credit card at the time of check-in and the amount of the stay will be authorized. The inn does not accept cash at check-in, but guests can pay cash upon check-out.

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