Red Roof PLUS+ Gainesville Red Roof Inn Plus Gainesville

3500 Southwest 42nd Street, Gainesville, FL   Directions
(565 Reviews)
Check in time
Check out time

Ready to book? Give us a call at 1-937-328-1598 .

Hotel Overview

NEED TO SPEAK TO THE FRONT DESK? Call 1-352-336-3311

Adding more WOW to your stay! Red Roof PLUS+ Gainesville invites you to stay in our 100% smoke-free rooms as you experience all Gainesville has to offer. Located just three miles from the UF Health, VF Vet Hospital and the University of Florida. Close to all the sporting events: Swamp and O'Connel Center, football, basketball, archery, baseball, soccer, and drag racing. Enjoy the many features of the property including flat screen TVs, free Wi-Fi, and free local and long distance telephone calls in all rooms. There are many dining options nearby.

...Read More

Click here to experience more of Gainesville.

Experience Red Roof PLUS+. Adding more WOW to your stay! Discover an enhanced experience with our most requested higher-end amenities. Red Roof PLUS+ Gainesville, Florida is a 100% smoke-free, pet-friendly, family friendly hotel. This hotel is close to I-75 at exit 384, the University of Florida, Santa Fe College, Kanapa Botanical Gardens, the Fred Bear Museum, the Performing Arts Center, Thr Florida Museum of Natrual History, Samuel Harn Museum of Art, Millhopper Devils Geological site, Hippodrome State Theatre, Gainesville Auto Plus Raceway, Oaks Mall, Butler Shopping Centers, UF Health, North Florida Regional Hospital, UF Vet Hospital and the VA Hospital.

As our guest you will experience our NextGen® design rooms! The rooms at this 100% smoke-free inn feature a stylish, boutique design furniture, spa-inspired bathrooms with modern vessel sinks, comfy Rest Suite beds by Serta, plush high-end bedding, modern design flooring, comfortable seating and a large, flat screen TV. This Red Roof PLUS+ hotel also features Premium Rooms with breakfast and a snack ready in your room! Red Roof PLUS+ Gainesville offers an outdoor pool that is open year around and select rooms offer microwave and mini-refrigerator units. This location includes interior corridors, an elevator, and suites. Experience our free coffeehouse-style coffee and tea. Stay connected with free Wi-Fi and keep your valuables secure in our in-room safe. This location offers “On Command Video” with a selection of free TV channels, pay-to-view premium channels, movies, music and games. We welcome your pet as a guest and one well behaved pet stays free. Welcome to Gainesville and we invite you to be our guest at the Red Roof PLUS+ Gainesville.

Learn more about Red Roof PLUS+ Gainesville!

Current Deals at this Location


Room & Rates

Your Search
, ,

Select Location

Special Rate
click for terms and conditions

red hot deals® are available below. they're our way of saying

thanks for visiting us!

Advanced Purchase rate is available below. Save on our best available rate when you book your stay in advance. Terms and conditions apply.

You selected 0 rooms, but we only have 0 rooms available
No results were found on Detail Page

Key Amenities

100% Smoke Free
Kids and Pets Stay Free
Verified Wi-Fi

Hotel Amenities

  • Free Coffee in the Lobby
  • Free Expanded Cable
  • Free Long Distance
  • Bilingual/Multilingual Staff
  • Swimming Pool
  • 100% Smoke-Free
  • ADA Accessible Parking
  • ADA Accessible Rooms
  • Airport within 10 Miles
  • Elevator
  • Interior Corridoors
  • Portable Cribs Available
  • Restaurant within Walking Distance
  • Snack Center
  • Free Parking


  • Target (0.18 mi)
  • Florida Museum Of Natural Historty (1.44 mi)
  • Curtis M. Phillips Center for the Performing Arts (1.46 mi)
  • Harn Museum of Art (1.51 mi)
  • Kanapaha Botanical Gardens (1.43 mi)
  • University of Florida (2.49 mi)
  • UF Veterinary Hospitals (2.38 mi)
  • Malcom Randall VA Medical Center (2.75 mi)
  • Stephen C. O'Connell Center (2.95 mi)
  • Ben Hill Griffin Stadium (3.06 mi)
  • Gainesville Regional Airport (GNV) (8.02)  mi
  • Menchie's Frozen Yogurt (0.38)  mi
  • Culver's (0.36)  mi
  • Jimmy John's (0.38)  mi
  • Pizza Hut Express (0.18)  mi
  • Steak 'n Shake (0.14)  mi
  • Maple Street Biscuit Company - Gainesville (0.37)  mi
  • Arby's (0.26)  mi
  • Miller's Ale House - Gainesville (0.29)  mi
  • McDonald's (0.24)  mi
  • Texas Roadhouse (0.38)  mi

TripAdvisor Ratings

Great service during hurricane
September 15, 2017

Arrived early in the morning after leaving home at 3:30 am and while there were no rooms ready yet, they managed to get us in before the official check-in time of 3 pm. All of the staff were friendly and helpful under stressful conditions, being inundated with people without reservations, desperate to find a room. The rooms were clean and updated and uncluttered and the beds were low enough to be reached by our small dog, which was a great plus. Stayed again after Irma on our return home and got the same very good treatment. They even managed to move the reservation one day earlier, making our drive home easier. Well done, staff.

Huge thank you for help during Hurricane Irma
September 11, 2017

I want to personally thank Monica and Dennis at Red Roof inn Plus in Gainesville for your kindness, patience and extra effort during a very trying time for my family this weekend. We had to evacuate at the last minute from Tampa sue to Hireicane Irma and they were so accommodating and friendly. They went out of their way to make sure we were comfortable and helped us book for an additional night and stay in the same room during a very crowded and tense situation. The room was supe clean and perfectly met our needs with our dog. Thank you again for all you did to help so many people this weekend. My daughter is a student at UF and we will be bac to visit her and will stay with you from now on! 🙂

July 29, 2017

This was a very nice hotel. Very clean and very comfortable. The staff was very helpful and friendly and always had time to take a few minutes to talk or answer any questions you may may have. The front desk people that I dealt with were also very helpful and nice. The room was nice and large and the air conditioning works great. Very quiet even though it is right next to I 75. HOTEL IS 100% NON SMOKING SO IF YOU WANT TO SMOKE YOU HAVE TO GO OUTSIDE BUT FOR SOME REASON THEY DON'T HAVE ASHTRAYS. WOULD DEFINITELY STAY HERE AGAIN!!!

Clean, good location and price
July 22, 2017

We used to live in Gainesville and any time we go to visit or travel by we stay at this location. The price is usually very reasonable usually in the $100 range and the rooms are always clean. The location is just off I-75 and is near Butler Plaza which has several grocery stores, Target, Wal-Mart, and many food options.

Always a great experience!
July 11, 2017

I have stayed at this Red roof several times while visiting my elderly parents in northern Florida. The inn is always very clean, always the best value in the area and the staff is exceptional. I had booked two rooms on 7/10/17 because my adult daughter was with me. Gloria greeted me like an old friend and completed the registration process very quickly. When I came back by the desk a few minutes later she was vacuuming the lobby and Crystal was at the desk. I made a comment about how everyone in the inn does whatever job they need to do and how impressed I was with all of them. Crystal was quick to let me know how much they appreciated my positive comments and asked if there was anything else she could do for me. When I came back in after dinner she was at the desk acknowledged me as I walked through the lobby. An amazing place with amazing people.

Return To Top
See Terms & Policies

Check-in Age: 18 years or older

Pet Policy: One well-behaved family pet is permitted, at no additional charge. Pet must be declared during guest registration and kept on a leash when outside guest room. In consideration of all guests, pets must never be left unattended in the guest room. When you walk your pet on the property, please be considerate and clean up after your pet.

Safe Usage Fee of $1.50 + tax per night will be added at the hotel

Special Policy: All guest must present a valid credit card at the time of check-in and the amount of the stay will be authorized. The inn does not accept cash at check-in, but guests can pay cash upon check-out.

RediCard Members

Forgot your password?
Join Redicard

Start Earning Rewards with Your First Stay

The fastest way to free nights and other rewards!

View all program details



Sign In Help

Forgot your username or password? No problem. We can email you information for updating this.

If you need further assistance, please call us at 1-800-733-7663

Contact Information (Optional)

Enter your other contact info now and save time when you book reservations.