Welcome to Red Roof Inn Durham – Duke Univ Medical Center, your affordable hotel near downtown Durham, NC. Our 100% smoke free hotel is conveniently located off I-85, offering comfortable accommodations at a value price for medical visitors, university guests, and travelers.

We offer our guests free Verified Wi-Fi, a free expanded cable package featuring HBO, and free coffee in the lobby. Every room includes a flat-screen TV, and select rooms feature a microwave, mini-refrigerator, in-room coffee, hair dryer, and an iron with ironing board for your convenience. We are proud to be a pet-friendly hotel, so your four-legged companion is always welcome. 

Red Roof Inn Durham – Duke Univ Medical Center places you close to Durham's premier destinations. Whether you're visiting loved ones at Duke University, exploring hands-on exhibits at the Museum of Life and Science, discovering native plants at the North Carolina Botanical Garden, supporting students at Durham School of the Arts, or teeing off at Hillandale Golf Course, our convenient location makes everything readily accessible.